Honda Motor Company's first four-wheeled vehicle was the T360 mini pickup truck, introduced in 1963. A few months later, the S500 roadster was introduced and produced for about a year. The S500 was preceded by a S360 prototype and succeeded by larger S600 and S800 models.
As befits a Honda, the S500 was technically interesting, with a 9500 rpm redline engine and final chain drive.
https://en.wikipedia.org/wiki/Honda_S500