I put a large hole in a Goodyear OE runflat on my X3 a while back and it was repaired without any issue by a local General Tire store. However, they did tell me that some of the early runflats were unrepairable due to their design. As explained to me, those had some sort of dense foam inserts bonded to the inside of the carcass that precluded access needed for interior patching.
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