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I feel like if Peter Attia were here he'd just say, guys, please, eat clean and do the work. The real hack is just those things, and if you don't believe it, just ask anyone if they do a hack for more than 1-2-5-8 years. They don't. These hacks are bull. They're an idea to quicken the pace usually, when real change takes decades. Meh.
Genetic issues are a different story, low TRT early on, for example, but most of this stuff just isn't needed if your diet and workout is in check.
My contribution to this thread is prolonged caloric restriction. Sit down to a huge dinner, eat about 1/3rd of it, get up, walk around the house 5 times at a medium pace and you'll no longer be hungry, and you'll suppress your insulin response.
Win/Win
As far as muscle, more stimulus is better; work your muscles every day you possibly can, just not to the point of pain or failure. Medium weight, medium reps, short sets, just keep the muscle stimulated and the food you eat will do the rest.
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